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PROTEIN KINASE C-EPSILON
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DeCS
Descriptor
English
:
Protein Kinase C-epsilon
Descriptor
Spanish
:
Proteína Quinasa C-epsilon
Descriptor
Portuguese
:
Proteína Quinase C-épsilon
Tree Number:
D08.811.913.696.620.682.700.725.750
Definition
English
:
A
protein kinase C
subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by
PHORBOL ESTERS
and
DIACYLGLYCEROLS
. It is targeted to specific cellular compartments in response to extracellular signals that activate
G-PROTEIN-COUPLED RECEPTORS
;
TYROSINE
KINASE RECEPTORS; and intracellular protein
tyrosine
kinase.
History Note
English
:
2006(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50723
Unique Identifier:
D051744
Occurrence in VHL
:
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DeCS
CID-10
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